Ben Stiller

Mel Coplin

Patricia Arquette

Nancy Coplin

Téa Leoni

Tina Kalb

Mary Tyler Moore

Pearl Coplin

George Segal

Ed Coplin

Alan Alda

Richard Schlichting

Lily Tomlin

Mary Schlichting

Richard Jenkins

Paul Harmon

Josh Brolin

Tony Kent

Celia Weston

Valerie Swaney

Glenn Fitzgerald

Lonnie Schlichting

Beth Stern

Jane

Cynthia Lamontagne

Sandra

David Patrick Kelly

Fritz Boudreau

John Ford Noonan

Mitch

Nadia Dajani

Jill

Don Creech

Cop #1

Tori Davis

Flight Attendant

Shawn Michael Howard

Roger

Suzanne Snyder

Alternative Wife (unconfirmed)