Freddie Highmore

Arthur Montgomery

Mia Farrow

Daisy Suchot

Adam LeFevre

Davido

Doug Rand

Arthur's Father

Penny Balfour

Rose Montgomery

Ron Crawford

Archibald Suchot

Madonna

Princess Selenia (voice)

David Bowie

Maltazard (voice)

David Suchet

Narrator (voice)

Robert De Niro

King (voice)

Snoop Dogg

Max (voice)

Lee Delong

Saleslady

Saul Jephcott

Police Officer #1

Christian Erickson

Antique Dealer

Oxmo Puccino

Mover #2

Robert William Bradford

Baliff

Jerry Di Giacomo

Repairman

Tonio Descanvelle

Police Officer #2

Chazz Palminteri

Travel Agent (voice)

Jimmy Fallon

Betameche (voice)

Emilio Estevez

Ferryman (voice)

Harvey Keitel

Miro (voice)

Rob Corddry

Seides (voice)

Nate Corddry

Seides (voice)

Erik Per Sullivan

Baby Bug/Mino (voice)

Anthony Anderson

Koolomassai (voice)

Jason Bateman

Darkos (voice)