Isabela Merced

Dora

Jeffrey Wahlberg

Diego

Madeleine Madden

Sammy

Eugenio Derbez

Alejandro Gutierrez

Michael Peña

Cole - Dora's Father

Eva Longoria

Elena

Benicio del Toro

Swiper (voice)

Madelyn Miranda

Dora (6 years)

Malachi Barton

Diego (6 years)

Dee Bradley Baker

Animal Vocalizations (voice)

Sasha Toro

Backpack (voice)

Marc Weiner

Map (voice)

Joey Vieira

Nico

Pia Miller

Sabrina - Diego's Mother

Adriana Barraza

Abuela Valerie

Damien Garvey

Security Guard

Nicholas Coombe

Randy

Tivon Toito'ona

Soccer Team Kid 1

Emily Bell

Soccer Team Kid 4

Jace Fleming

Mean Kid

Matthew Okine

Teacher

Natasa Ristic

Christina X

Christopher Kirby

Viper

Temuera Morrison

Powell

Isela Vega

Old Woman

Danny Trejo

Boots (voice)

Q'orianka Kilcher

Kawillaka

Joel Murphy

High School Dancer

Kristin Sparks

High School Dancer

Savannah La Rain

High School Dancer

Caleb McLaughlin

Tico (voice)

Vanesa Everett

Mixed Nationality Tourist (uncredited)