Mary McDonnell

May-Alice Culhane

Alfre Woodard

Chantelle

Vondie Curtis-Hall

Sugar LeDoux

David Strathairn

Rennie

Leo Burmester

Reeves

Nora Dunn

Ti-Marie

Mary Portser

Precious

Angela Bassett

Rhonda / Dawn

Sheila Kelley

Kim

Nancy Mette

Nina

Lenore Banks

Nurse Quick

Michael Mantell

Dr. Kline

Daniel Dupont

Therapist #3

Maggie Renzi

Louise

Marianne Muellerleile

Drushka

Amanda Carlin

Perky

Tom Wright

Luther

Michael Laskin

Redwood Vance

John Sayles

Soap Opera Doctor (uncredited)