Casey Affleck

Pete Kepler

Kate Hudson

Skye Davidson

Brendan Sexton III

Blue Baxter

Christina Ricci

Ely Jackson

Ethan Suplee

Cale

Sara Gilbert

Sandy

Peter Sarsgaard

Billy Baxter

John Heard

Prof. Lance Davidson

Isidra Vega

Haley Gordon

Rene Rivera

Dr. Gordon

Lucinda Jenney

Caroline Baxter

Daniel von Bargen

Sheriff Jackson

Michael Ironside

Agent Frank Bellows

Aunjanue Ellis-Taylor

Agent Summers

Liev Schreiber

Mickey Moonday (voice)

Richmond Arquette

Truck Driver

Ntare Guma Mbaho Mwine

Agent Green