Robert De Niro

The Creature / Sharp Featured Man

Kenneth Branagh

Victor Frankenstein

Tom Hulce

Henry Clerval

Helena Bonham Carter

Elizabeth

Aidan Quinn

Cap. Robert Walton

Ian Holm

Baron Frankenstein

Richard Briers

Grandfather

John Cleese

Prof. Waldman

Robert Hardy

Prof. Krempe

Cherie Lunghi

Caroline Beaufort Frankenstein

Celia Imrie

Mrs. Moritz

Mark Hadfield

Felix

Gerard Horan

Claude

Richard Clifford

Minister

George Asprey

Policeman

Hugh Bonneville

Schiller

Ryan J-W Smith

William

Rory Jennings

Young Victor

Hannah Taylor-Gordon

Young Elizabeth

Jimmy Yuill

Greigori

Shaun Prendergast

Ship's Crew

David Kennedy

Ship's Crew

Alex Lowe

Ship's Crew

Jenny Galloway

Vendor's Wife

Peter Jonfield

Rough Man

Edward Jewesbury

City Official

Siobhan Redmond

Midwife

Michael Gould

Stablehand

Angus Wright

Guard

Jim Carter

Executioner (uncredited)