Ian McKellen

Sherlock Holmes

Laura Linney

Mrs. Munro

Milo Parker

Roger

真田広之

Tamiki Umezaki

Roger Allam

Dr. Barrie

Frances de la Tour

Madame Schirmer

Hattie Morahan

Ann Kelmot

Phil Davis

Inspector Gilbert

Patrick Kennedy

Thomas Kelmot

John Sessions

Mycroft Holmes

Frances Barber

Matinee "Madame Schirmer"

Charles Maddox

Oswald

Takako Akashi

Maya Umezaki

Michael Culkin

Bank Manager

Oliver Devoti

Ticket Agent

Nicholas Rowe

Matinee "Sherlock Holmes"

Hermione Corfield

Matinee "Ann Kelmot"

Kit Connor

Boy

Zoe Rainey

Boy's Mother

Eileen Davies

Lady on Platform

Sarah Crowden

Mrs. Hudson

Johnny Otto

Army Officer (uncredited)