Robert De Niro

Frank Goode

Drew Barrymore

Rosie

Kate Beckinsale

Amy

Sam Rockwell

Robert

Melissa Leo

Colleen

Damian Young

Jeff

James Frain

Tom

Kate Moennig

Jilly

Brendan Sexton III

Mugger

James Murtaugh

Dr. Ed

Austin Lysy

David

Lily Mo Sheen

Young Amy

Seamus Davey-Fitzpatrick

Young Robert

Lucian Maisel

Jack

Ben Schwartz

Writer

Kene Holliday

Butcher

E.J. Carroll

Wine Man

Lou Carbonneau

BBQ Salesman

Mandell Butler

Delivery Man

Katy Grenfell

Young Woman on First Train

Lynn Cohen

Old Woman on First Train

Jayne Houdyshell

Alice

Kelly McAndrew

Hooker

Jason Harris

Cab Rider #1

Julián Rebolledo

Cab Rider #2

Lynn Blades

Anchorwoman

Kevin Collins

Anchorman

Debargo Sanyal

Art Director

Scott Cohen

Music Conductor

Erica Leigh Boseski

Female Orchestra Member

Mimi Lieber

Jean Goode (voice)

Mattie Hawkinson

Art Gallery Girl