Randy Quaid

Eddie Johnson

Miriam Flynn

Catherine Johnson

Dana Barron

Audrey Griswold

Jake Thomas

Third Johnson

Sung-Hi Lee

Muka Laka Miki

Julian Stone

Melbourne Jack

Beverly Garland

Aunt Jessica

Stephen Furst

Hospital Doctor

Rodger Bumpass

Lab Visitor / Plumber (voice) / Air Controller (voice)

Eric Idle

English Victim

Fred Willard

Professor Doornitz

Ed Asner

Uncle Nick

Kate Simmons

Paige

Trish Suhr

Woman (Next to Nick on Plane)