Chevy Chase

Clark Griswold

Beverly D'Angelo

Ellen Griswold

Anthony Michael Hall

Rusty Griswold

Imogene Coca

Aunt Edna

Randy Quaid

Cousin Eddie

Dana Barron

Audrey Griswold

Eddie Bracken

Roy Walley

Brian Doyle-Murray

Kamp Komfort Clerk

Miriam Flynn

Cousin Catherine

James Keach

Motorcycle Cop

Eugene Levy

Car Salesman

Frank McRae

Grover

John Candy

Lasky, Guard at Walleyworld

Christie Brinkley

Girl In The Red Ferrari

Jane Krakowski

Cousin Vicki

John P. Navin, Jr.

Cousin Dale

Nathan Cook

Man Giving Directions

Mickey Jones

Mechanic

John Diehl

Assistant Mechanic

Randy Lowell

Wyatt Earp

Gerry Black

Davenport

James Staley

Motel Desk Clerk

Tessa Richarde

Motel Guest

Michael Talbott

Cowboy

Henry Gibson

Hotel clerk (uncredited)

Harold Ramis

Car salesman (voice) (uncredited)