Michael J. Fox

Stuart Little (voice)

Geena Davis

Mrs. Little

Hugh Laurie

Mr. Little

Jonathan Lipnicki

George Little

Nathan Lane

Snowbell (voice)

Melanie Griffith

Margalo (voice)

James Woods

Falcon (voice)

Steve Zahn

Monty (voice)

Marc John Jefferies

Will

Angelo Massagli

Wallace

Jim Doughan

Soccerball Coach

Brad Garrett

Plumber

Conan McCarty

Referee

Maria Bamford

Teacher

Dyllan Christopher

Kid

Ronobir Lahiri

Cab Driver

Frank Aquilino

Onlooker

Rachael Harris

Additional Voices (voice)