Freddie Highmore

Arthur Montgomery

Madonna

Princess Selenia (voice)

Mia Farrow

Daisy Suchot

Jimmy Fallon

Betameche (voice)

David Bowie

Maltazard (voice)

Doug Rand

Arthur's Father

Penny Balfour

Rose Montgomery

Ron Crawford

Archibald Suchot

David Suchet

Narrator (voice)

Jason Bateman

Prince Darkos (voice)

Adam LeFevre

Davido

Robert De Niro

King (voice)

Snoop Dogg

Max (voice)

Lee Delong

Saleslady

Saul Jephcott

Police Officer #1

Christian Erickson

Antique Dealer

Oxmo Puccino

Mover #2

Robert William Bradford

Baliff

Jerry Di Giacomo

Repairman

Tonio Descanvelle

Police Officer #2

Emilio Estevez

Ferryman

Harvey Keitel

Miro

Rob Corddry

Seides

Nate Corddry

Seides

Erik Per Sullivan

Baby Bug / Mino (voice)

Chazz Palminteri

Travel Agent (voice)

Anthony Anderson

Koolomassai (voice)