Nicolas Cage

Frank Pierce

Patricia Arquette

Mary Burke

John Goodman

Larry Verber

Ving Rhames

Marcus

Tom Sizemore

Tom Wolls

Marc Anthony

Noel

Mary Beth Hurt

Nurse Constance

Cliff Curtis

Cy Coates

Aida Turturro

Nurse Crupp

Nestor Serrano

Dr. Hazmat

Sonja Sohn

Kanita

Larry Fessenden

Cokehead

Arthur J. Nascarella

Captain Barney

Martin Scorsese

Dispatcher (voice)

Queen Latifah

Dispatcher Love (voice)

Michael Kenneth Williams

Drug Dealer

Craig muMs Grant

Voice in Crowd

John Heffernan

Mr. Oh

Judy Reyes

ICU Nurse

Afemo Omilami

Griss

Julyana Soelistyo

Sister Fetus

Graciela Lecube

Neighbor Woman

Marylouise Burke

Neighbor Woman

Phyllis Somerville

Mrs. Burke

Tom Riis Farrell

John Burke

Aleks Shaklin

Arguing Russian

Leonid Citer

Arguing Russian

Fuschia!

Prostitute

Matthew Maher

Mr. Oh's Friend

Don Berry

Naked Man

Omar Scroggins

Bystander

Andy Davoli

Stanley

Jesse Malin

Club Doorman

Jon Abrahams

Club Bystander

Lia Yang

Dr. Milagros

Antone Pagán

Arrested Man

Melissa Marsala

Bridge & Tunnel Girl

Betty Miller

Weeping Woman

Sylva Kelegian

Crackhead

Catrina Ganey

Nurse Odette

Tom Cappadona

Drunk

Jack O'Connell

Drunk

Richard Spore

Homeless Suicidal

James Hanlon

Fireman

Michael Mulheren

Cop in Elevator

David Zayas

Cop in Elevator

Terry Serpico

Cop #1

Joseph P. Reidy

ICU Doctor

Carolyn Campbell

Policewoman (uncredited)

Michael Carbonaro

Club Kid (uncredited)

Brian Smyj

Cop #2 (uncredited)