Michael J. Fox

Chance (voice)

Sally Field

Sassy (voice)

Don Ameche

Shadow (voice)

Kevin Chevalia

Jamie Seaver

Benj Thall

Peter Burnford

Veronica Lauren

Hope Burnford

Kim Greist

Laura Burnford-Seaver

Robert Hays

Bob Seaver

Jean Smart

Kate

Gary Taylor

Frank

Ted D'Arms

Vet

Don Alder

Molly's Father

Ed Bernard

Desk Sergeant

William Phipps

Quentin

Frank Welker

Special Vocal Effects (voice)

Bart the Bear

Bear

Kit McDonough

Female Forest Ranger

Caroll Spinney

Dog in Pound (uncredited)

Mark L. Taylor

Officer Kirkwood