Henry Thomas

Elliott

Drew Barrymore

Gertie

Robert MacNaughton

Michael

Peter Coyote

Keys

Dee Wallace

Mary

Erika Eleniak

Pretty Girl

K.C. Martel

Greg

C. Thomas Howell

Tyler

Sean Frye

Steve

Milt Kogan

Medical Unit

Mary Stein

Medical Unit

Mitch Suskin

Medical Unit

Ted Grossman

Government Agent (uncredited)

James Kahn

Mustachioed Medical Unit Member Who Confirms E.T.'s Death (uncredited)

Anne Lockhart

Nurse (uncredited)

Melissa Mathison

Elliot's School Nurse (uncredited)

Debra Winger

Nurse Zombie Carrying Poodle (uncredited)

Michael Lepre

Pizza Man (uncredited)

Quinn Smith

Kid 3 (uncredited)