Madison Iseman

Rain Burroughs

Israel Broussard

Caleb

Eugenie Bondurant

Dani McConnell

Katherine Heigl

Michelle Burroughs

Harry Connick Jr.

John Burroughs

Julia Vasi

Alexa

Enuka Okuma

Dr. Elyn Pangloss

Jannette Sepwa

Nurse Rosa

Bianca D'Ambrosio

Cinda

Brian Yang

Dr. Yang

Lindsay Lamb

Cam

Todd Goble

Vice Principal

Keil Oakley Zepernick

The Man with Yellow Eyes

Isabella Abiera

Voices in Rain's Head (voice)

Elvia Hill

Medical Student