Lupita Nyong'o

Adelaide Wilson / Red

Winston Duke

Gabe Wilson / Abraham

Elisabeth Moss

Kitty Tyler / Dahlia

Tim Heidecker

Josh Tyler / Tex

Shahadi Wright Joseph

Zora Wilson / Umbrae

Evan Alex

Jason Wilson / Pluto

Yahya Abdul-Mateen II

Russell Thomas / Weyland

Anna Diop

Rayne Thomas / Eartha

Cali Sheldon

Becca Tyler / Io

Noelle Sheldon

Lindsey Tyler / Nix

Madison Curry

Young Adelaide Wilson / Young Red

Napiera Groves

Dr. Foster

Duke Nicholson

Danny / Tony

Dustin Ybarra

Troy / Brand

Kara Hayward

Nancy / Syd

Jordan Peele

Dying Rabbit / Fun House Narrator (voice) (uncredited)

Darrel Cherney

News Anchor (uncredited)

Alessandro Garcia

EMT (uncredited)