Gabourey Sidibe

Precious

Mo'Nique

Mary

Paula Patton

Ms. Rain

Mariah Carey

Ms. Weiss

Sherri Shepherd

Cornrows

Lenny Kravitz

Nurse John

Stephanie Andujar

Rita

Chyna Layne

Rhonda

Amina Robinson

Jermaine

Xosha Roquemore

Joann

Angelic Zambrana

Consuelo

Nealla Gordon

Mrs. Lichenstein

Kimberly Russell

Katherine

Bill Sage

Mr Wicher

Abigail Savage

Bunny

Rodney "Bear" Jackson

Carl

AzMarie Livingston

Girl with Jermaine

Mugga

KFC Cashier

Chazz Menendez

Man #1 Exits Elevator (St)

Roy T. Anderson

Man #2 Exits Elevator (St)

Erica Faye Watson

Sheila

Ephraim Benton

Skinny Boy #1

Alex Manette

Administrator Harris (uncredited)