Julian Sands

Dr. Nick Cavanaugh

Sherilyn Fenn

Helena

Bill Paxton

Ray O'Malley

Art Garfunkel

Dr. Lawrence Augustine

Kurtwood Smith

Dr. Alan Harrison

Nicolette Scorsese

Fantasy Lover / Nurse

Meg Register

Marion Cavanaugh

Carl Mazzocone Sr.

Pastor

Ted Manson

Mailman

D. Taylor Loeb

Laura (uncredited)