James Cagney

Tom Powers

Jean Harlow

Gwen Allen

Edward Woods

Matt Doyle

Joan Blondell

Mamie

Donald Cook

Mike Powers

Leslie Fenton

Samuel 'Nails' Nathan

Beryl Mercer

Ma Powers

Robert Emmett O'Connor

Paddy Ryan

Murray Kinnell

Putty Nose

Mae Clarke

Kitty (uncredited)

Frank Coghlan Jr.

Tom as a Boy (uncredited)

Frankie Darro

Matt as a Boy (uncredited)

Snitz Edwards

Miller (uncredited)

Rita Flynn

Molly Doyle (uncredited)

Douglas Gerrard

Assistant Tailor (uncredited)

Ben Hendricks Jr.

'Bugs' Moran as a Boy (uncredited)

Robert Homans

Officer Pat Burke (uncredited)

Eddie Kane

Joe - Headwaiter (uncredited)

Sam McDaniel

Headwaiter (uncredited)

Helen Parrish

Little Girl (uncredited)

Lee Phelps

Steve - Bartender (uncredited)

Russ Powell

Bartender (uncredited)

Purnell Pratt

Officer Powers (uncredited)

Joe Sawyer

Pool Player (uncredited)

Landers Stevens

Doctor (uncredited)

William H. Strauss

Pawnbroker (uncredited)

Charles Sullivan

Mug (uncredited)

Lucille Ward

Mrs. Dalton (uncredited)

Adele Watson

Mrs. Doyle (uncredited)