Ben Stiller

Greg Focker

Robert De Niro

Jack Byrnes

Teri Polo

Pam Byrnes

Blythe Danner

Dina Byrnes

Nicole DeHuff

Debbie Byrnes

Jon Abrahams

Denny Byrnes

Owen Wilson

Kevin Rawley

James Rebhorn

Dr. Larry Banks

Tom McCarthy

Dr. Bob Banks

Phyllis George

Linda Banks

Kali Rocha

Flight Attendant

Bernie Sheredy

Norm the Interrogator

Judah Friedlander

Pharmacy Clerk

Peter Bartlett

Animal Shelter Worker

John Elsen

Chicago Airport Security

Amy Hohn

Ticket Agent

John Fiore

Kinky

Frank Santorelli

Courier

Russell Hornsby

Late Night Courier

Cody Arens

Little Boy

Cole Hawkins

Little Boy

Spencer Breslin

Little Boy

Kresh Novakovic

Airport Policeman

John Joseph Gallagher

Cop

G.A. Aguilar

Cop