Samuel L. Jackson

Afro / Ninja-Ninja (voice)

Grey DeLisle

Tomoe / Ogin (voice)

Mark Hamill

Bin / Oden Shop Master (voice)

Greg Eagles

Afro's Father (voice)

Lucy Liu

Sio (voice)

Kevin Michael Richardson

Blacksmith / Takimoto (voice)

Steve Blum

Man A / Assassins (voice)

Dave Wittenberg

Adolescent / Fencing Brother (voice)

Jeff Bennett

Brother 3 (voice)

Liam O'Brien

Shichogoro (voice)

Zachary Gordon

Kotaro (voice)

Phil LaMarr

Young Afro (voice)

Yuri Lowenthal

Jinno (voice)

RZA

DJ (voice)

Ariel Winter

Young Sio (voice)