Penelope Ann Miller

Dr. Margo Green

Tom Sizemore

Lt. Vincent D'Agosta

Linda Hunt

Dr. Ann Cuthbert

James Whitmore

Dr. Albert Frock

Clayton Rohner

Det. Hollingsworth

Chi Muoi Lo

Dr. Greg Lee

Robert Lesser

Mayor Robert Owen

Diane Robin

The Mayor's Wife

Lewis van Bergen

John Whitney

Constance Towers

Mrs. Harriet Blaisedale

Francis X. McCarthy

Mr. George Blaisedale

Audra Lindley

Dr. Matilda Zwiezic

John Kapelos

McNally

Tico Wells

Bailey

Mike Bacarella

Bradley

Gene Davis

Martini

David Proval

Guard Johnson

Jophery C. Brown

Guard Frederick Ford

Don Harvey

Spota

Santos Morales

Capt. Borne

Ralph Seymour

Sergeant

Lyn Alicia Henderson

Perri Masai

Brian Steele

Kothoga

Amanda Ingber

Donna

Eddie Jemison

Museum Worker

Kurt Naebig

Police Officer

Ken Magee

Coroner's Assistant

Aaron Lustig

Dr. Brown

Ron Cummins

Dr. Gross

Gary A. Hecker

Kothoga (voice)

Craig Hosking

Helicopter Pilot

Dana Kristen Vahle

Helicopter Pilot

Dick Warlock

Policeman (uncredited)