Matt Dillon

Bob

Kelly Lynch

Dianne

James Remar

Gentry

James Le Gros

Rick

Heather Graham

Nadine

Beah Richards

Drug Counselor

Grace Zabriskie

Bob's Mother

Max Perlich

David

William S. Burroughs

Tom the Priest

Eric Hull

Druggist

George Catalano

Trousinski

Ted D'Arms

Neighbor Man

Gus Van Sant

Himself (uncredited)