James D'Arcy

Sherlock Holmes

Roger Morlidge

Dr. Watson

Vincent D'Onofrio

Moriarty

Gabrielle Anwar

Rebecca Doyle

Richard E. Grant

Mycroft

Nicholas Gecks

Inspector Lestrade

Struan Rodger

Ben Harrington

Peter-Hugo Daly

Henry Coot

Mihai Bisericanu

Sgt. Cox

Sandu Mihai Gruia

Dr. Cruickshank

Ioana Abur

Victoria

Valentin Popescu

Killer

Anca Androne

Nurse