Ron Fazio

The Toxic Avenger / Apocalypse Inc. Executive

John Altamura

The Toxic Avenger

Phoebe Legere

Claire

Rick Collins

Apocalypse Inc. Chairman

安岡力也

Big Mac

関根勤

Announcer

桂木麻也子

Masami

Lisa Gaye

Malfaire

Jessica Dublin

Mrs. Junko

Michael Jai White

Apocalypse Inc. Executive

Joe Fleishaker

Apocalypse Inc. Executive

Dan Snow

Cigarface

Charlotte Kaufman

Blind Baby

Lily Hayes Kaufman

Toxic Child

Lisbeth Kaufman

Toxic Child

Lloyd Kaufman

Sumo Wrestler / Fish Salesman (voice)

永井豪

Tsukudani Expert

Paul Borghese

Lou Sipher (uncredited)

Scott Leva

The Dark Rider (uncredited)

Maya Shiraki

Chain-Sickle Girl