Jodie Foster

Clarice Starling

Anthony Hopkins

Dr. Hannibal Lecter

Scott Glenn

Jack Crawford

Ted Levine

Jame Gumb

Anthony Heald

Dr. Frederick Chilton

Brooke Smith

Catherine Martin

Diane Baker

Senator Ruth Martin

Kasi Lemmons

Ardelia Mapp

Frankie Faison

Barney

Tracey Walter

Lamar

Charles Napier

Lt. Boyle

Danny Darst

Sgt. Tate

Dan Butler

Roden

Paul Lazar

Pilcher

Ron Vawter

Paul Krendler

Roger Corman

FBI Director Hayden Burke

Lawrence T. Wrentz

Agent Burroughs

Stuart Rudin

Miggs

Maria Skorobogatov

Young Clarice

Gene Borkan

Oscar

Pat McNamara

Sheriff Perkins

Kenneth Utt

Dr. Akin

Adelle Lutz

TV Anchor Woman

Obba Babatundé

TV Anchor Man

George Michael

TV Sportscaster

Cynthia Ettinger

Officer Jacobs

Brent Hinkley

Officer Murray

David Early

Spooked Memphis Cop

Andre B. Blake

Tall Memphis Cop

Chris Isaak

SWAT Commander

Daniel von Bargen

SWAT Communicator

Harry Northup

Mr. Bimmel

Lauren Roselli

Stacy Hubka

Ted Monte

FBI Agent (uncredited)

George A. Romero

FBI Agent in Memphis (uncredited)

John W. Iwanonkiw

Orderly (uncredited)

Robert W. Castle

Priest on Chilton's Plane (uncredited)

Chris McGinn

Autopsy Victim (uncredited)

Gary Goetzman

Guido Paonessa (uncredited)