Rob Lowe

John F. Kennedy

Will Rothhaar

Lee Harvey Oswald

Ginnifer Goodwin

Jacqueline Kennedy

Michelle Trachtenberg

Marina Oswald

Jack Noseworthy

Robert F. Kennedy

Casey Siemaszko

Jack Ruby

Jamie McShane

Richard Snyder

Mary Pat Gleason

Marguerite Oswald

Boris McGiver

John Fain

Antoinette LaVecchia

Lady Bird Johnson

Francis Guinan

Lyndon B. Johnson

Richard Flood

Kenny O'Donnell

Jody Matzer

Lead Trauma Surgeon

Boris McGiver

FBI Agent

Brian Hutchison

Winston Lawson

Peter Rini

Agent Mooney

Danny McCarthy

Agent James Hosty

Natalie Gold

Ruth Paine

Juan Pablo Veizaga

Carlos Bringuier

William L. Thomas

Clint Hill

Angelo Reyes

First Cuban

Terry Menefee Gau

Nurse Doris Nelson

Bonnie Johnson

Earlene Roberts

Demosthenes Chrysan

George De Mohrenschildt

Pete Burris

John Quigley

L. Derek Leonidoff

Marion Baker

Robert C. Treveiler

Sheriff's Deputy

Christopher Wiehl

Agent O'Reilly

Mike Marunde

Mike

Taylor Roberts

Faddle

Joseph Gray

Sergeant Gerald Hill

Bo Keister

Tony - Bartender

Lucas N. Hall

Officer Atwell, Dallas P.D.