George Clooney

Jack Foley

Jennifer Lopez

Karen Sisco

Ving Rhames

Buddy Bragg

Don Cheadle

Maurice 'Snoopy' Miller

Steve Zahn

Glenn Michaels

Dennis Farina

Marshall Sisco

Catherine Keener

Adele Delisi

Isaiah Washington

Kenneth

Albert Brooks

Richard Ripley

Luis Guzmán

José 'Chino' Chirino

Viola Davis

Moselle

Nancy Allen

Midge

Keith Hudson

Bank Cop

Brad Martin

White Boxer

James Black

Himey

Wendell B. Harris Jr.

Daniel Burdon

Chuck Castleberry

Library Guard

Chic Daniel

Shock Lock FBI Man

Keith Loneker

White Boy Bob

Connie Sawyer

Old Elevator Lady

Paul Calderon

Raymond Cruz

Mark Brown

Ripley Personnel

Wayne Pére

Philip

Joe Chrest

Andy

Joe Coyle

Third Ad Guy

Michael Keaton

Ray Nicolette (uncredited)

Samuel L. Jackson

Hejira Henry (uncredited)

Jennifer Dorogi

Waitress (uncredited)

Deborah Smith Ford

Airport Passenger (uncredited)

Thelma Gutiérrez

Flight Attendant (uncredited)

Wayne V. Johnson

Bank Manager (uncredited)

Pati Lauren

Bank Patron (uncredited)