Diane Morgan

Philomena Cunk

Douglas Hedley

Self

Rupert Sheldrake

Self

Paul Nurse

Self

Jim Al-Khalili

Self

Ruth Adams

Self

Brian Cox

Self

Michelle Greenidge

Jacqui Flink

Charles Aitken

Waylon Jackalope IV

Genevieve Gaunt

Puppet (voice)

Kat Kumar

Puppet (voice)

Atlanta Johnson

Eve

Greg Lockett

Doll Advert Voice Over (voice)

Charlie Brooker

BBC Announcer (voice) (uncredited)